CBD roj thiab hemp extracts

Tsis ntev los no, qhov nrov ntawm kev npaj cannabis tau nce ntau heev. Kev koom tes nrog cannabis tuaj yeem pab txhawb rau ib feem ntawm qhov kev xav no. Txawm li cas los xij, muaj kev cai lij choj hemp extracts thiab CBD roj tsis zoo ib yam li tshuaj maj vim lawv tsis muaj THC intoxicating. Hauv cov ntawv no, peb yuav teb cov lus nug nram qab no: hemp yog dab tsi, CBD roj yog dab tsi, lawv tau txais li cas, paub dab tsi txog lawv cov txiaj ntsig rau tib neeg lub cev?

Dr. N. Pharm. Maria Kaspshak

Lus Cim: Cov ntawv no yog siv rau cov ntaub ntawv xov xwm, tsis yog kev kho tus kheej, tsis yog thiab tsis tuaj yeem hloov tus neeg sab laj nrog kws kho mob!

Hemp yog ib tsob nroj uas tau cog rau ntau pua xyoo

Hemp, lossis Cannabis sativa, yog ib tsob nroj cog qoob loo uas pom thoob plaws ntiaj teb. Raws li nrog txhua kab lis kev cai, muaj ntau hom kab mob thiab ntau yam ntawm cannabis, txhua tus muaj lawv tus yam ntxwv sib txawv. Hemp tau cog rau ntau pua xyoo rau cov fibers siv los ua hlua, hlua thiab hlua, nrog rau cov ntaub (li no ntau yam ntawm hemp). Cov roj hemp tau nias los ntawm cov noob, uas tau siv rau cov khoom noj thiab kev lag luam - piv txwv li, rau kev tsim cov xim thiab cov kua roj vanish. Hauv qhov no, hemp muaj kev siv tib yam li flax (uas tseem yog cog rau fiber ntau thiab oilseeds), thiab ua ntej paj rwb tau qhia rau Tebchaws Europe, flax thiab hemp yog qhov tseem ceeb ntawm cov nroj tsuag fibers rau khaub ncaws thiab lwm yam khoom. Qhov tseeb nthuav yog tias ua ntej kev sib kis ntawm rapeseed cultivation nyob rau hauv teb chaws Poland, nws yog hemp roj, ib sab ntawm linseed roj thiab, tsawg zaus, poppy noob roj, uas yog cov feem ntau nrov zaub roj nyob rau hauv lub Polish countryside. Kev noj cov roj zaub yog nrov tshwj xeeb tshaj yog thaum Advent thiab Lent, thaum tsiaj rog tau yoo mov thiab tsis noj.

Hemp, hemp, tshuaj maj - dab tsi yog qhov txawv?

Tam sim no, hemp yog qhov txaus siab ua cov nroj tsuag tshuaj. Tshwj xeeb tshaj yog nyob rau hauv no hais txog yog poj niam inflorescences, nplua nuj nyob rau hauv biologically active tshuaj, feem ntau cannabinoids (los yog: cannabinoids) thiab terpenes. Cov khoom muaj lub luag haujlwm rau cov nyhuv narcotic ntawm cannabis yog delta-9-tetrahydrocannabinol (THC), uas yog cov tshuaj intoxicating uas ua rau muaj kev xav ntawm euphoria, so, kev hloov hauv kev xaav ntawm kev muaj tiag, thiab lwm yam. Vim li no, THC thiab cannabis uas muaj. ntau tshaj 0,2 .XNUMX% THC nyob rau hauv cov nqe lus ntawm qhuav qhov hnyav, lawv suav hais tias yog ib qho tshuaj nyob rau hauv teb chaws Poland, thiab lawv muag thiab siv yog txhaum cai.

Cannabis (Cannabis sativa subsp. Indica, cannabis) muaj cov ntsiab lus siab ntawm THC. Cannabis ntau yam uas muaj qis qis ntawm THC raug cais raws li kev lag luam hemp (Cannabis sativa, hemp), tsis muaj zog, thiab lawv cov qoob loo thiab muag tsis txwv. Txawm hais tias cannabis thiab kev lag luam cannabis yog ntau yam ntawm tib hom, lossis ob hom sib cais, tsis muaj kev pom zoo tag nrho, tab sis rau cov neeg siv nruab nrab, kev faib cov botanical tsis yog qhov tseem ceeb tshaj plaws.

Cannabinoids thiab terpenes yog phytochemicals pom hauv cannabis

Cannabis sativa muaj cov lej ntawm THC, tab sis muaj lwm yam sib xyaw ua ke xws li cannabinoids (los yog cannabinoids), suav nrog CBD - cannabidiol (cannabidiol) thiab terpenes, piv txwv li. tshuaj pom nyob rau hauv ntau cov nroj tsuag nrog ib tug yam ntxwv, qab ntxiag tsw. CBD tsis muaj zog rau tib neeg thiab tsis muaj tshuaj lom. Cov cannabinoids thiab terpenes ntawm cannabis yog cov nquag nquag nyob rau hauv cov plaub hau glandular uas loj hlob ntawm cov poj niam inflorescences. Lawv qhov zais cia, thiab cov hemp resin uas muaj cov khoom sib txuas no, yog cov nplaum heev thiab muaj peev xwm tiv thaiv cov nroj tsuag kom qhuav thiab kev loj hlob microbial yog puas.

Terpenes, xws li pinenes, terpineol, limonene, linalool, myrcene (thiab ntau lwm yam) yog cov tebchaw pom tsis tau tsuas yog nyob rau hauv cannabis, tab sis kuj nyob rau hauv ntau lwm yam nroj tsuag, tshwj xeeb tshaj yog cov uas muaj zog aroma. Lawv yog cov khoom xyaw hauv ntau cov roj yam tseem ceeb thiab cov tshuaj tsw qab, nrog rau cov tshuaj tsw qab ntxiv rau cov tshuaj pleev ib ce. Qee tus ntawm lawv muaj cov tshuaj tua kab mob uas tswj kev zom zaub mov thiab tso kua tsib (piv txwv li, alpha thiab beta pinene). Txawm li cas los xij, lawv tuaj yeem ua rau muaj kev fab tshuaj, yog li cov neeg ua xua yuav tsum siv lawv nrog ceev faj.

Kev kho cov teebmeem ntawm cannabinoids - kev npaj muaj THC thiab CBD

Cannabinoids ua rau tib neeg lub cev los ntawm lub npe hu ua cannabinoid receptors, pom nyob rau hauv tshwj xeeb hauv lub paj hlwb thiab hauv cov hlwb ntawm lub cev tiv thaiv kab mob. Cov receptors no yog ib feem ntawm ib qho ntawm "kev sib txuas lus thiab kev tswj hwm txoj hauv kev" hauv lub cev, zoo li opioid receptors thiab lwm yam. Lub endocannabinoid system nyob rau hauv lub cev tswj ib tug xov tooj ntawm physiological zog xws li mus ob peb vas thiab qab los noj mov, raws li zoo raws li lub cev tiv thaiv kab mob thiab cuam tshuam lub endocrine system. Tetrahydrocannabinol (THC) cuam tshuam rau cov receptors hauv lub hlwb, ua rau, ntawm lwm yam, kev xav ntawm intoxication. Cannabidiol (CBD) zoo li muaj kev cuam tshuam me ntsis ntawm cannabinoid receptors, tab sis kuj rau lwm tus, xws li histamine. Tej zaum nws kuj hloov cov teebmeem ntawm THC.

 Anabinoids tau pom lawv daim ntawv thov hauv tshuaj. Ib qho tshuaj uas muaj THC hluavtaws, dronabinol, tau pom zoo los ntawm US FDA kom yooj yim ntuav thiab txhim kho qab los noj mov hauv cov neeg mob AIDS thiab mob qog noj ntshav. Sativex muaj THC thiab CBD muaj nyob rau hauv teb chaws Poland thiab tau qhia rau kev kho mob ntawm spasticity (cov leeg nqaij ntau dhau) hauv cov neeg mob uas muaj ntau yam sclerosis. Epidiolex yog ib qho kev pom zoo tshiab uas muaj cov ntshiab CBD hauv cov roj noob hnav, qhia rau kev kho mob ntawm qee yam mob vwm rau cov menyuam yaus - Dravet syndrome thiab Lennox-Gastaut syndrome. Nws tseem tsis tau muaj nyob hauv tebchaws Poland.

Hemp roj thiab CBD roj - lawv muaj dab tsi thiab lawv tau txais li cas?

Cov roj hemp yog cov roj hemp noob roj. Lawv yog cov khoom noj muaj txiaj ntsig, muaj lub saj qab ntxiag thiab muaj qhov tseem ceeb omega-3 thiab omega-6 unsaturated fatty acids nyob rau hauv ib qho piv txwv. Ntawm qhov tod tes, CBD roj feem ntau yog cov roj zaub (hemp los yog lwm yam) nrog rau ntxiv ntawm ib qho extract (extract) los ntawm ntsuab seem ntawm hemp - nplooj lossis paj. Thiab - vim lawv cov concentration - lawv saj tsis tas yuav qab ntxiag.

Ib qho ntawm cov khoom xyaw tseem ceeb ntawm cov extract no yog cannabidiol (CBD), yog li lub npe ntawm cov tshuaj no. Txawm li cas los xij, hemp extract kuj muaj lwm cov tshuaj cog (los yog phytochemicals, los ntawm Greek "phyton" - cog), piv txwv li, lwm yam cannabinoids, terpenes thiab ntau lwm yam tshuaj, nyob ntawm seb hom hemp siv thiab cov txheej txheem ntawm extraction, i.e. rho tawm. Cov neeg tsim khoom qee zaum sau "tag nrho spectrum" ntawm daim ntawv lo qhia tias tag nrho cov cannabis extract tau siv. Cov kuab tshuaj organic tuaj yeem siv tau rau kev tshem tawm, piv txwv li "kev ntxuav tawm" thiab cov ntsiab lus ntawm cov khoom siv cog qoob loo, vim tias cannabinoids thiab lwm yam phytochemicals tsis yaj hauv dej. Txoj kev no muaj nws qhov tsis zoo - cov kuab tshuaj residues tuaj yeem kis cov khoom tiav, thiab lawv cov seem yuav tsum tau muab pov tseg kom zoo. Yog vim li cas thiaj li hu ua supercritical CO2 extraction. Qhov no txhais tau tias siv cov kua carbon dioxide ua cov kuab tshuaj nyob rau hauv siab heev, i.e. nyob rau hauv lub thiaj li hu ua supercritical tej yam kev mob.

 Qhov no yog ib tug complex txhais nyob rau hauv lub teb ntawm physics ntawm lub cev lub xeev, tab sis qhov tseem ceeb rau peb yog cov kua carbon dioxide dissolves cov khoom uas tsis yaj nyob rau hauv dej, yog non-toxic thiab, nyob rau hauv ib txwm tej yam kev mob, evaporates yooj yim heev yam tsis muaj impurities. . Yog li, qhov kev rho tawm CO2 supercritical no yog ib txoj kev "huv" heev siv hauv kev lag luam tshuaj thiab zaub mov.

Tej zaum koj yuav tau nyeem txog CBD roj uas lawv yog "decarboxylated". Nws txhais li cas? Zoo, ntau cannabinoids yog tsim los ntawm cov nroj tsuag hauv daim ntawv acidic. Peb yuav nco ntsoov koj los ntawm lub rooj ntev zaum hauv tsev kawm ntawv tias pawg ntawm cov organic acids yog ib pawg carboxyl, lossis -COOH. Cua sov cov txiv hmab txiv ntoo qhuav los yog extract tshem tawm cov pab pawg no los ntawm cannabinoid molecule thiab tso tawm raws li carbon dioxide - CO2. Qhov no yog txheej txheem decarboxylation uas, piv txwv li, cannabidiol (CBD) tuaj yeem tau los ntawm cannabidiolic acid (CBD).

Cov roj CBD puas muaj txiaj ntsig zoo?

Puas yog hemp extracts, tshuaj ntsuab npaj lossis CBD roj tib yam li cov npe npaj, xws li Epidiolex muaj CBD? Tsis yog, lawv tsis zoo ib yam. Ua ntej, lawv tsis muaj THC. Thib ob, Epidiolex muaj cov ntshiab cannabidiol yaj hauv cov roj, uas tau raug sim rau cov koob tshuaj tshwj xeeb. CBD roj muaj tag nrho cov cocktail ntawm ntau yam cannabis tebchaw. Nws tsis paub yuav ua li cas muaj lwm yam phytochemicals hloov cov teebmeem ntawm cannabidiol rau lub cev. Ib lub tuam txhab CBD roj tuaj yeem muaj qhov sib txawv kiag li ntau dua li lwm tus, vim lawv tuaj yeem siv ntau hom hemp, ntau txoj hauv kev, thiab kev tswj kom zoo. Tsis tas li ntawd, qee qhov kev tshawb fawb txog kev noj zaub mov muaj roj CBD qhia tau hais tias cov ntsiab lus ntawm cannabidiol thiab lwm yam khoom xyaw yuav txawv ntawm cov neeg tsim khoom, txij li kev tswj hwm kev tsim khoom ntxiv tsis raug rau tib yam kev tswj hwm tshuaj ntau lawm. . Kuj tseem tsis tau muaj kev sim tshuaj txaus txaus kom paub meej tias cov khoom zoo ntawm CBD roj rau qee yam kab mob, yog li tseem tsis muaj cov koob tshuaj tas li uas tuaj yeem ua rau qee yam teebmeem.

Rau tag nrho cov laj thawj no, CBD roj tsis tuaj yeem suav tias yog tshuaj thiab nws tsis muaj tseeb tias, piv txwv li, Epidiolex yog tib yam li CBD roj. Ib yam li ntawd, willow bark tsis zoo ib yam li cov tshuaj aspirin. Qhov no tsis tau txhais hais tias CBD roj tsis cuam tshuam rau lub cev thiab tsis hloov cov tsos mob ntawm tus kab mob - muaj tsuas yog me ntsis txhim khu kev qha, cov ntaub ntawv pov thawj ntawm cov ncauj lus no.

Yuav siv CBD roj li cas kom nyab xeeb?

Txawm hais tias tsis muaj pov thawj ntawm kev kho mob ntawm cov teebmeem kev kho mob ntawm CBD roj, lawv muaj nyob rau hauv kev ua lag luam thiab tau dhau los ua neeg nyiam. Lawv tsis raug muag li tshuaj, tab sis ntau thiab ntau tus neeg xav sim lawv. Yog tias koj xaiv siv cov roj CBD, muaj ob peb txoj cai tseem ceeb uas yuav tsum nco ntsoov.

• Ua ntej tshaj plaws, nrhiav cov roj CBD zoo tshaj plaws los ntawm cov tuam txhab ntseeg siab. Nug txog cov xwm txheej ntawm cov khoom lag luam, daim ntawv pov thawj kev txheeb xyuas cov khoom, zoo dua ua los ntawm cov chaw kuaj thib peb.
• Qhov thib ob, nrog koj tus kws kho mob tham, tshwj xeeb tshaj yog tias koj noj tshuaj. Cannabidiol thiab phytochemicals tuaj yeem cuam tshuam nrog cov tshuaj kom txo lossis txhim kho lawv cov teebmeem lossis ua rau muaj kev phom sij. Muaj ntau cov nroj tsuag thiab tshuaj ntsuab uas cuam tshuam tsis zoo rau ntau yam tshuaj (xws li St. John's wort lossis grapefruit), yog li "natural" tsis tas txhais tau tias "muaj kev nyab xeeb nyob rau txhua qhov xwm txheej."
• Tshawb xyuas nrog koj tus kws kho mob kom pom tias noj CBD roj tuaj yeem pab tau. Hauv cov ntawv teev lus koj yuav pom cov peev txheej los pab koj txiav txim siab.
• Txiav txim seb tus nqi lossis kev noj cov roj uas koj noj nrog koj tus kws kho mob, tshwj xeeb tshaj yog tias koj xav txhawb kev tswj hwm kab mob ntev lossis noj lwm yam tshuaj. Thaum txiav txim siab cov roj uas koj noj, nco ntsoov tias muaj cov roj uas muaj cov ntsiab lus sib txawv CBD thiab cov concentration, xaiv ib qho kev npaj tshwj xeeb.
• Tshwj tsis yog tias koj tus kws kho mob tau hais rau koj, tsis txhob tshaj qhov ntau npaum li qhov pom zoo los ntawm cov chaw tsim khoom.
• Nco ntsoov tias cannabidiol thiab lwm yam phytochemicals kuj tuaj yeem ua rau muaj kev phom sij rau lub cev, tshwj xeeb tshaj yog thaum noj ntau lossis siv sijhawm ntev. Lawv tuaj yeem yog, ntawm lwm yam, tsaug zog, qaug zog, xeev siab, teeb meem nrog lub siab lossis lub raum. Tej zaum yuav muaj lwm yam dej num uas tsis paub rau peb vim kev tshawb fawb tsis txaus nyob hauv cheeb tsam no. Saib koj cov tshuaj tiv thaiv!
• Tsis txhob siv cov roj CBD yog tias koj muaj teeb meem hauv siab lossis raum, lossis yog tias koj cev xeeb tub lossis pub niam mis. Nco ntsoov nrog koj tus kws kho mob thaum muaj kev tsis ntseeg!
• Tsis txhob tso koj tus kws kho mob cov tshuaj kom pom zoo "kev kho tus kheej" CBD roj! Tshwj xeeb tshaj yog tias koj mob hnyav, xws li mob qog noj ntshav, mob hlwb lossis mob hlwb, koj yuav tsum tsis txhob ua qhov no. Koj tuaj yeem ua mob rau koj tus kheej ntau heev.

Cov Ntawv Hmoob

1. CANNABIDIOL (CBD), Daim Ntawv Ceeb Toom Tseem Ceeb, Pawg Kws Tshaj Lij Tshaj Lij rau Kev Tiv Thaiv Tshuaj, Lub Rooj Sib Tham Fortieth, Geneva, 4-7 Lub Rau Hli 2018 https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf (dostęp 04.01.2021)
2. Phau ntawv Journal of Laws 2005 No. 179, art. 1485, AWA Act of July 29, 2005 for counteracting drug addiction. Txuas mus rau txoj cai lij choj thiab lwm yam kev cai lij choj: https://www.kbpn.gov.pl/portal?id=108828 (hnub nkag: 04.01.2021/XNUMX/XNUMX)
3. Cov ntaub ntawv hais txog Sativex: https://www.mp.pl/pacjent/leki/lek/88409,Sativex-aerozol-do-stosowania-w-jamie-ustnej (Accessed: 04.01.2021/XNUMX/XNUMX)
4. Cov ntaub ntawv hais txog Epidiolex (ua lus Askiv): https://www.epidiolex.com (Accessed: 001.2021)
5. Cov ntawv sau qhia: VanDolah HJ, Bauer BA, Mauck KF. "Tus Kws Kho Mob Phau Ntawv Qhia rau Cannabidiol thiab Hemp Roj". Mayo Clean Proc. 2019 Sep; 94(9): 1840-1851 doi: 10.1016/j.mayocp.2019.01.003. Epub 2019, Aug 22. PIB: 31447137 https://www.mayoclinicproceedings.org/action/showPdf?pii=S0025-6196%2819%2930007-2 (dostęp 04.01.2021)
6. Arkadiusz Kazula "Kev siv cov cannabinoids ntuj thiab endocannabinoids hauv kev kho", Postępy Farmakoterapii 65 (2) 2009, 147-160

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